Brentwood had its first beginning in the year 1957 by a Pastor named John Chick. He and his family arrived from Missouri, driving a car and pulling a little trailor with all their belongings. They arrived in Roanoke with $2.47 in their pocket. Their first meeting place was a house on Oliver Avenue. From there, they began to use the VFW hall on Preston Avenue near Williamson Road. On July 23rd, 1961, Pastor Jesse Powell and wife Nilda arrived to take over the work. The work was organized by Central Baptist Church in Hampton, Virginia, where Brother Thornton Hall pastored. Property on Plantation Road was purchased from a farmer, and not long thereafter, ground was broken to build the building where Brentwood Baptist Church now stands. Brother Powell was here from 1961 until 2013. He retired from the pastorate when Pastor Ken Johnson came in 1998. Brother Johnson pastored for nine years and then had a series of strokes, for which cause he resigned from the ministry. From 2009 until 2013, Brother Powell stepped back in to act as pastor while the church prayed and sought another man. Brother Rodney Spears was called by the church in June of 2013. Before coming, he had to finish his missionary and deputation responsibilities which he did. Brother Spears first Sunday as pastor was October 6, 2013.